One of the most hilariously irreverent, popular characters in the Marvel Universe is Deadpool. With the ability to break the fourth-wall and the knowledge that he's a comic book character, the wisecracking Merc with a Mouth has mixed superhero action and slapstick comedy since his creation by Rob Liefeld and Fabian Nicieza 1991's New Mutants #98.

Starring in two hit feature films in addition to numerous appearances in animated series, video games and other merchandise, Deadpool has gained a legion of new fans. Since there are so many Deadpool comics out there, CBR has rounded up a selection of the best new-reader friendly comic book stories starring the Marvel mercenary.

RELATED: How Deadpool's Secret Secret Wars Put Wade Wilson in the Marvel Classic

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One of comics' greatest odd couples is the pairing of Deadpool and time-traveling mutant superhero Cable. The characters had originally served as antagonists in Deadpool's first appearance, with the mercenary actively hunting Cable, before becoming unlikely friends and allies and starring in their own fan-favorite team-up ongoing series.

Cable & Deadpool: If Looks Could Kill written by Nicieza and illustrated by Mark Brooks and Patrick Zircher collects the first story arc in the duo's long-running series. which sees the mismatched pair navigate their complicated friendship, with plenty of high-octane action to bond over.

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In Deadpool's earliest appearances, he battled the New Mutants and their leader Cable as a much more serious character than the nonsensical goofball approach that would largely become associated with the character in subsequent depictions.

RELATED: How Deadpool Got the Infinity Gauntlet (and What He Did With It)

Deadpool Classic Vol. 1 collects Wade Wilson's first appearances, from his introduction taking a contract out on Cable to both his 1993 and 1994 miniseries that placed the Merc with a Mouth in a starring role and gradually marked his shift into a more comedic character without compromising his lethal edge. While he's not quite the motor-mouthed character you know and love until the end of this volume, it's still a worthwhile, action-packed comic book introduction to Wade Wilson.

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In the '90s, writer Joe Kelly became one of the definitive voices behind Deadpool through his extensive work with the character, The acclaimed, veteran comic scribe has written the ongoing adventures of Wade Wilson in the Marvel Universe in memorably hijinks-filled tales off-and-on for decades and is credited for many of the more wacky aspects of the character including his ability to break the fourth wall.

Deadpool Classic Vol. 2 contains the start of Kelly's longtime association with the character from Deadpool's unlikely team-up with the Incredible Hulk to the Merc with a Mouth's encounters with the mutant Siryn and Daredevil villain Typhoid Mary, illustrated by artists like Ed McGuinness, Kevin Lau and Pete Woods.

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Another fan-favorite writer who put her signature zany spin on Deadpool is Gail Simone. Teamed with artist UDON, the creative team brought both the high stakes and outrageous jokes to the character's popular ongoing series. The run would be referenced several times in the 2016 Deadpool film, including Wade's use of scooter as his primary transportation and Simone being directly name-dropped in the film.

RELATED: How Captain America and Deadpool Formed Marvel's Strangest Friendship

Deadpool Classic Vol. 9 collects the start Simone and UDON's run on the character including the Agent X spinoff series starring a gun-toting figure labeled by Deadpool as his possible doppelgänger from an alternate reality that had arrived in the Marvel Universe. Despite the volume's number, this remains a fan-favorite run that works perfectly as a starting place.

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Longtime comedy writers Gerry Duggan and Brian Posehn teamed with The Walking Dead co-creator Tony Moore to relaunch Deadpool's ongoing series for a well-received, best-selling run that put Wade in the center of escalating antics in the heart of the Marvel Universe.

The creative team's first story arc, Deadpool: Dead Presidents, had the Merc with a Mouth confront zombified versions of the former President of the United States at one time, now undead and united in a sinister plot to retake the country to reshape it in their image. Teamed with the ghost of Benjamin Franklin, the tale had Deadpool take down each former Commander-in-Chief by any means necessary with hilarious results.

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